Lightning + Sea Dog + Skulkers = Max Damage
I have been using the combination of Lightning + Sea Dog + Skulkers for a few weeks now, and have found it extremely useful against strong single opponents. I've also used it to blast through the Bottomless Cave without taking any damage.
When Sea Dog is Ganged Up, if you use Skulkers' Tricksy Trick on him, the first hit is 35%, but the second hit is full power.
Against a single opponent, first hit it with Skulkers to get the 30% damage multiplier. In the Bottomless Cave, apply Tricksy Trick on Skulkers so both pigs have the multiplier.
If you have the Golden Chili, use it on Lightning. You'll get 2 hits with Lightning, 1 hit with Skulkers (a good amount of damage), and 3 hits with Sea Dog.
Then, on the next turn, using Lightning's Lightning Fast and Skulkers' Tricksy Trick, you can get 5 full power hits with Sea Dog, plus 1 35% hit. That's a devastating amount of damage. Over 2 turns, it's much more powerful than Wizard + Pirate + Skulkers.
When dealing with pigs that charge up for 3 turns, if you have a spare turn where you won't take damage, make sure Sea Dog stays Ganged Up.
I've also used this combination on Wave Pool to knock out Spirit Caller 7 or 8 times in 10 waves. When you have the rested bonus, it's a good way to level up your birds in a hurry. You also get around 160 snoutlings. If your spin gets the treasure chest, you get two Greater Vials, needed for Pig Cherry Juice.